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Nano eNabler™ Molecular Printing System

The Nano eNabler™ system is a highly flexible molecular printer that can dispense minute volumes of liquid at defined positions to create patterns of spots or lines with high spatial accuracy. The system is based on BioForce's proprietary FEMTO (Fluidics Enhanced Molecular Transfer Operation) process. This technology enables the deposition of the 1-30 um sample droplets quickly, precisely and with reduced clogging.

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Product Description

The core of the Nano eNabler system is a compact precision motion control platform mated to a microfabricated surface patterning tool (SPT™) with integrated microfluidics. Molecules to be printed are loaded into the SPT™ reservoirs by pipet for the ultimate in simplicity. A variable intensity laser and position-sensitive photodetector are employed to monitor the contact time and force between the SPT™ cantilever and the surface being patterned. In this way, the user is able to precisely control the volume of liquid being dispensed and the resulting feature size. Sophisticated electronics and a powerful user interface provide millisecond control over each deposition event. To ensure consistent printing, a constant humidity is maintained by an environmental chamber and computer-controlled humidifier. The entire process can be viewed through a high resolution optical zoom microscope and CCD camera with video displayed within the NanoWare™ software. To minimize the instrument’s footprint, the computer has been integrated into the controller.

Technical Specifications

  • Spot size: 1-50 microns (attoliter to femtoliter)
  • XY Travel: 50 mm
  • XY Resolution: 20 nm
  • Printing cycle: 100ms
  • Z Range: 50mm
  • Z Resolution: 100nm
  • Optical Zoom: 100x – 700x

Features

  • Built-in optical microscope
  • Control software
  • Multiplexing ability
  • Line writing (beta)
  • Environmental control
  • Video recording
  • Image capture
  • On the fly pattern design

Benefits

Larger patterns: 250,000 times more XY patterning area than Scanning Probe Lithography systems
Faster printing: Direct molecular deposition via FEMTO does not rely on diffusion
Less frustration: Open channel SPT(TM) print cartridges exhibit less clogging than ink-jets or nano-pipettes
More capabilities: Superior alignment and multiplexing compared to microcontact printing
Greater flexibility: Make design changes in software without new photomasks or PDMS molds

Materials

Proteins
Nucleic Acids
Lipids
Colloids
Quantum Dots
UV-curable Adhesives
Etchants
Catalysts

Surfaces

Silicon
Silanes
Metals
Alkanethiol Monolayers
PDMS
Hydrogels
Nitrocellulose
Polystyrene

Videos

View all product videos here.